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Target
DNA gyrase inhibitor
Ligand
BDBM635616
Substrate
n/a
Meas. Tech.
SDFQ HTS Assay
IC50
1560±n/a nM
Citation
 LENG, F; ALFONSO, E; DENG, Z; NEFZI, A; ROHDE, K BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF US Patent  US20230364057 Publication Date 11/16/2023 
Target
Name:
DNA gyrase inhibitor
Synonyms:
SBMC_ECOLI | gyrI | sbmC | yeeB
Type:
Protein
Mol. Mass.:
18071.67
Organism:
n/a
Description:
P33012
Residue:
157
Sequence:
MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
 
Inhibitor
Name:
BDBM635616
Synonyms:
US20230364057, Compound 178
Type:
Small organic molecule
Emp. Form.:
C15H12N4O4S
Mol. Mass.:
344.345
SMILES:
COc1cc(\C=N\N=c2/[nH]c3ccccc3s2)cc(c1O)[N+]([O-])=O
Structure:
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