Reaction Details Report a problem with these data
Target
Nuclear receptor coactivator 2 [740-753]
Ligand
BDBM205025
Substrate
n/a
Meas. Tech.
Homogeneous Time-Resolved Fluorescence (HTRF) assay
IC50
<1000±0 nM
Citation
 Xiao, D; Li, J; Zhu, Y; Hu, Y; Wang, H; Wang, Z; Wang, Z; Wei, Y; Sun, Y; Wu, Q; Zhang, H; Peng, Y; Kong, F; Sun, Y; Luo, H; Han, Y Kinase modulating compounds, compositions containing the same and use thereof US Patent  US9550781 Publication Date 1/24/2017 
Target
Name:
Nuclear receptor coactivator 2 [740-753]
Synonyms:
BHLHE75 | Human nuclear receptor coactivator 2 (aa 740-753) | NCOA2 | NCOA2_HUMAN | Nuclear receptor coactivator 2 (aa 740-753) | SRC2 | SRC2-3 peptide | TIF2
Type:
fluorescent labeled peptide
Mol. Mass.:
1704.90
Organism:
n/a
Description:
Q15596 aa 740-753
Residue:
14
Sequence:
KENALLRYLLDKDD
 
Inhibitor
Name:
BDBM205025
Synonyms:
US9550781, 22 | n-(3-(3-(9h-purin-6-yl)pyridin-2-ylamino)-2,4-difluorophenyl)-2-(4-methoxyphenyl)cyclopropane-1-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C26H21F2N7O3S
Mol. Mass.:
549.552
SMILES:
COc1ccc(cc1)C1CC1S(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F
Structure:
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