Target

Ligand

Substrate

Meas. Tech.

Human A1 Adenosine Receptor Binding Assay

Ki

>10000±n/a nM

Citation

 Cosimelli, B; Greco, G; Ehlardo, M; Novellino, E; Da Settimo, F; Taliani, S; La Motta, C; Bellandi, M; Tuccinardi, T; Martinelli, A; Ciampi, O; Trincavelli, ML; Martini, C Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists. J Med Chem 51:1764-70 (2008) [PubMed]  Article Copy BDB DOI

More Info.:

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Name:

Adenosine receptor A2a

Synonyms:

A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

44716.46

Organism:

Homo sapiens (Human)

Description:

P29274

Residue:

412

Sequence:

MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS

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Blast E-value cutoff:

Name:

BDBM21218

Synonyms:

2,5,8-trimethyl-4,7-dihydro-1H-benzo[1,2-d:3,4-d :5,6-d ]triimidazole | 4,9,14-trimethyl-3,5,8,10,13,15-hexaazatetracyclo[10.3.0.0^{2,6}.0^{7,11}]pentadeca-1(12),2(6),3,7(11),8,13-hexaene | CHEMBL200480 | benzotriimidazole, D

Type:

Small organic molecule

Emp. Form.:

C12H12N6

Mol. Mass.:

240.2639

SMILES:

Cc1nc2c([nH]1)c1nc(C)[nH]c1c1nc(C)[nH]c21

Structure:

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Similarity to this molecule at least:

Name:

BDBM21241

Synonyms:

Adenosine, N6-Ethyl-carboxamido | Adenosine-5 -(N-ethylcarboxamide) | N-Ethylcarboxamidoadenosine | [3H]NECA

Type:

n/a

Emp. Form.:

n/a

Mol. Mass.:

n/a

SMILES:

n/a

Structure: