Target
Galectin-3
Ligand
BDBM21542
Substrate
BDBM21520
Meas. Tech.
Fluorescence Polarization Assay
pH
7.2±n/a
Temperature
297.15±n/a K
Kd
2800000±800000 nM
Citation
 Oberg, CTLeffler, HNilsson, UJ Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors. J Med Chem 51:2297-301 (2008) [PubMed]  Article 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM21542
Synonyms:
Galactose-Derived Compound 20 | [(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(methylsulfanyl)oxan-3-yl]oxidanesulfonic acid
Type:
n/a
Emp. Form.:
C7H14O8S2
Mol. Mass.:
290.311
SMILES:
CS[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1OS(O)(=O)=O
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM21520
Synonyms:
fluorescein-tagged saccharide
Type:
fluorescent probe
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
n/a
Structure: