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Target
Vitamin D-binding protein
Ligand
BDBM36717
Substrate
n/a
Meas. Tech.
DBP Binding Assay
pH
7.4±0
Temperature
277.15±0 K
IC50
200±0.0 nM
Citation
 Boehm, MF; Fitzgerald, P; Zou, A; Elgort, MG; Bischoff, ED; Mere, L; Mais, DE; Bissonnette, RP; Heyman, RA; Nadzan, AM; Reichman, M; Allegretto, EA Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3. Chem Biol 6:265-75 (1999) [PubMed]  Article 
Target
Name:
Vitamin D-binding protein
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
52955.57
Organism:
Homo sapiens (Human)
Description:
ChEMBL_622880
Residue:
474
Sequence:
MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPKELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL
  
Inhibitor
Name:
BDBM36717
Synonyms:
1,25(OH)2D3
Type:
Small organic molecule
Emp. Form.:
C30H50O
Mol. Mass.:
426.7174
SMILES:
CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C |r|
Structure:
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