Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37731
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37731
Synonyms:
2-(6-amino-5-cyano-4-cyclohex-2-en-1-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)acetic acid methyl ester | 2-[6-amino-5-cyano-4-(1-cyclohex-2-enyl)-2,4-dihydropyrano[2,3-c]pyrazol-3-yl]acetic acid methyl ester | MLS000043507 | SMR000020324 | cid_3242657 | methyl (6-amino-5-cyano-4-cyclohex-2-en-1-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)acetate | methyl 2-(6-amino-5-cyano-4-cyclohex-2-en-1-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)acetate | methyl 2-(6-azanyl-5-cyano-4-cyclohex-2-en-1-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)ethanoate
Type:
Small organic molecule
Emp. Form.:
C16H18N4O3
Mol. Mass.:
314.3391
SMILES:
COC(=O)Cc1n[nH]c2OC(=N)C(C#N)C(C3CCCC=C3)c12 |c:20|
Structure:
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