Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM37838
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Ki
>40300±n/a nM
Comments
Extracted from aid = 520 and tid = 2
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM37838
Synonyms:
2-[[6-ethyl-4-keto-3-(1-methylbenzimidazol-2-yl)-7-pivaloyloxy-chromen-2-yl]methoxy]acetic acid | 2-[[7-(2,2-dimethyl-1-oxopropoxy)-6-ethyl-3-(1-methyl-2-benzimidazolyl)-4-oxo-1-benzopyran-2-yl]methoxy]acetic acid | 2-[[7-(2,2-dimethylpropanoyloxy)-6-ethyl-3-(1-methylbenzimidazol-2-yl)-4-oxidanylidene-chromen-2-yl]methoxy]ethanoic acid | 2-[[7-(2,2-dimethylpropanoyloxy)-6-ethyl-3-(1-methylbenzimidazol-2-yl)-4-oxochromen-2-yl]methoxy]acetic acid | MLS000530991 | SMR000135969 | cid_1325504 | {[7-[(2,2-dimethylpropanoyl)oxy]-6-ethyl-3-(1-methyl-1H-benzimidazol-2-yl)-4-oxo-4H-chromen-2-yl]methoxy}acetic acid
Type:
Small organic molecule
Emp. Form.:
C27H28N2O7
Mol. Mass.:
492.5204
SMILES:
CCc1cc2c(cc1OC(=O)C(C)(C)C)oc(COCC(O)=O)c(-c1nc3ccccc3n1C)c2=O |(15.91,-4.32,;15.92,-2.78,;14.59,-2,;13.19,-2.79,;11.82,-1.97,;11.82,-.43,;13.19,.4,;14.59,-.4,;15.92,.38,;15.91,1.92,;14.58,2.68,;17.24,2.69,;18.57,3.47,;16.47,4.02,;18.02,1.36,;10.48,.34,;9.15,-.43,;7.82,.34,;7.82,1.88,;6.48,2.65,;6.48,4.19,;5.15,4.96,;7.82,4.96,;9.15,-1.97,;7.82,-2.74,;6.42,-2.11,;5.39,-3.25,;3.85,-3.25,;3.08,-4.58,;3.85,-5.92,;5.39,-5.92,;6.16,-4.58,;7.66,-4.26,;8.8,-5.29,;10.48,-2.74,;10.48,-4.28,)|
Structure:
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