Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50067906
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7±0
Ki
7.3e+3±n/a nM
Citation
 Tondi, D; Powers, RA; Caselli, E; Negri, MC; Blázquez, J; Costi, MP; Shoichet, BK Structure-based design and in-parallel synthesis of inhibitors of AmpC beta-lactamase. Chem Biol 8:593-611 (2001) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM50067906
Synonyms:
(3-aminophenyl)boronic acid, 1 | 3-aminophenyl boronic acid | 3-aminophenylboronic acid | Aza-boronic acid derivative | Boronic acid derivative | CHEMBL20852 | M-AMINOPHENYLBORONIC ACID
Type:
Small organic molecule
Emp. Form.:
C6H8BNO2
Mol. Mass.:
136.944
SMILES:
Nc1cccc(c1)B(O)O
Structure:
Search PDB for entries with ligand similarity: