Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM40446
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Ki
>44300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM40446
Synonyms:
N-(2-furanylmethyl)-2-methyl-N-(8-quinolinylsulfonyl)propanamide | N-(2-furfuryl)-2-methyl-N-(8-quinolylsulfonyl)propionamide | N-(furan-2-ylmethyl)-2-methyl-N-quinolin-8-ylsulfonyl-propanamide | N-(furan-2-ylmethyl)-2-methyl-N-quinolin-8-ylsulfonylpropanamide | UNM000003607701 | cid_6458820
Type:
Small organic molecule
Emp. Form.:
C18H18N2O4S
Mol. Mass.:
358.412
SMILES:
CC(C)C(=O)N(Cc1ccco1)S(=O)(=O)c1cccc2cccnc12
Structure:
Search PDB for entries with ligand similarity: