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Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31018
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists
EC50
>40000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31018
Synonyms:
2-(4,6-diaminopyrimidin-2-yl)sulfanyl-N-(4-phenylbutan-2-yl)acetamide | 2-[(4,6-diamino-2-pyrimidinyl)thio]-N-(4-phenylbutan-2-yl)acetamide | 2-[(4,6-diaminopyrimidin-2-yl)thio]-N-(1-methyl-3-phenyl-propyl)acetamide | 2-[4,6-bis(azanyl)pyrimidin-2-yl]sulfanyl-N-(4-phenylbutan-2-yl)ethanamide | MLS000254508 | SMR000068242 | cid_3000091
Type:
Small organic molecule
Emp. Form.:
C16H21N5OS
Mol. Mass.:
331.436
SMILES:
CC(CCc1ccccc1)NC(=O)CSc1nc(N)cc(N)n1
Structure:
Search PDB for entries with ligand similarity: