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Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31069
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Antagonists
IC50
>50000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31069
Synonyms:
5-bromanyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]furan-2-carboxamide | 5-bromo-N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)-2-furamide | 5-bromo-N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-2-furamide | 5-bromo-N-[4-(2-oxazolo[4,5-b]pyridinyl)phenyl]-2-furancarboxamide | 5-bromo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]furan-2-carboxamide | MLS000061716 | SMR000070185 | cid_1161055
Type:
Small organic molecule
Emp. Form.:
C17H10BrN3O3
Mol. Mass.:
384.184
SMILES:
Brc1ccc(o1)C(=O)Nc1ccc(cc1)-c1nc2ncccc2o1
Structure:
Search PDB for entries with ligand similarity: