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Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31074
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Antagonists
IC50
>39000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31074
Synonyms:
MLS000062611 | N-(6-methoxy-8-quinolinyl)-4-methylbenzenesulfonamide | N-(6-methoxy-8-quinolyl)-4-methyl-benzenesulfonamide | N-(6-methoxyquinolin-8-yl)-4-methyl-benzenesulfonamide | N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide | SMR000071147 | cid_130606
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3S
Mol. Mass.:
328.386
SMILES:
COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: