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Target
Mitogen-activated protein kinase 10
Ligand
BDBM42747
Substrate
n/a
Meas. Tech.
Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3)
IC50
5586±n/a nM
Citation
 PubChem, PC Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) PubChem Bioassay (2008)[AID] 
Target
Name:
Mitogen-activated protein kinase 10
Synonyms:
JNK3 | JNK3A | MAP kinase p49 3F12 | MAPK10 | MK10_HUMAN | Mitogen-Activated Protein Kinase 10 (JNK3) | Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) | Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 | PRKM10 | SAPK1B | Stress-activated protein kinase JNK3 | c-Jun N-terminal kinase 3 (JNK3)
Type:
Enzyme
Mol. Mass.:
52586.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
464
Sequence:
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
  
Inhibitor
Name:
BDBM42747
Synonyms:
2-ethoxy-N-[3-[[3-(2-hydroxyethylsulfonyl)anilino]-oxomethyl]phenyl]-3-pyridinecarboxamide | 2-ethoxy-N-[3-[[3-(2-hydroxyethylsulfonyl)phenyl]carbamoyl]phenyl]nicotinamide | 2-ethoxy-N-[3-[[3-(2-hydroxyethylsulfonyl)phenyl]carbamoyl]phenyl]pyridine-3-carboxamide | 2-ethoxy-N-{3-[({3-[(2-hydroxyethyl)sulfonyl]phenyl}amino)carbonyl]phenyl}nicotinamide | MLS000094592 | SMR000030145 | cid_3243903
Type:
Small organic molecule
Emp. Form.:
C23H23N3O6S
Mol. Mass.:
469.51
SMILES:
CCOc1ncccc1C(=O)Nc1cccc(c1)C(=O)Nc1cccc(c1)S(=O)(=O)CCO
Structure:
Search PDB for entries with ligand similarity: