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Target
RAC-alpha serine/threonine-protein kinase
Ligand
BDBM32354
Substrate
n/a
Meas. Tech.
AKT counterscreen of confirmed PKD inhibitors-57K library
IC50
>100000±n/a nM
Citation
 PubChem, PC AKT counterscreen of confirmed PKD inhibitors-57K library PubChem Bioassay (2008)[AID] 
Target
Name:
RAC-alpha serine/threonine-protein kinase
Synonyms:
AKT phosphorylation (p-AKT) | AKT1 | AKT1/PPP1CA | AKT1_HUMAN | C-AKT | PKB | PKB alpha | Protein kinase Akt-1 | Protein kinase B | Protein kinase B (AKT1) | Protein kinase B (Akt 1) | Protein kinase B (Akt) | Protein kinase B alpha | Protein kinase B alpha (AKT1) | Proto-oncogene Akt (Akt1) | Proto-oncogene c-Akt (AKT) | Proto-oncogene c-Akt (AKT1) | RAC | RAC-PK-alpha | RAC-alpha serine/threonine-protein kinase (AKT) | RAC-alpha serine/threonine-protein kinase (AKT1) | RAC-alpha serine/threonine-protein kinase (pAKT)
Type:
Enzyme
Mol. Mass.:
55681.25
Organism:
Homo sapiens (Human)
Description:
P31749
Residue:
480
Sequence:
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
  
Inhibitor
Name:
BDBM32354
Synonyms:
4-(cyclohexanecarbonyl)-1H-pyrrole-2-carboxylic acid | 4-(cyclohexylcarbonyl)-1H-pyrrole-2-carboxylic acid | 4-[cyclohexyl(oxo)methyl]-1H-pyrrole-2-carboxylic acid | 4-cyclohexylcarbonyl-1H-pyrrole-2-carboxylic acid | MLS000736313 | SMR000338263 | cid_1482736
Type:
Small organic molecule
Emp. Form.:
C12H15NO3
Mol. Mass.:
221.2524
SMILES:
OC(=O)c1cc(c[nH]1)C(=O)C1CCCCC1
Structure:
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