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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43768
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43768
Synonyms:
1-(3,4-Dichloro-phenyl)-3-thiazol-2-yl-urea | 1-(3,4-dichlorophenyl)-3-(1,3-thiazol-2-yl)urea | 1-(3,4-dichlorophenyl)-3-(2-thiazolyl)urea | 1-(3,4-dichlorophenyl)-3-thiazol-2-yl-urea | MLS000529419 | SMR000121894 | cid_722640
Type:
Small organic molecule
Emp. Form.:
C10H7Cl2N3OS
Mol. Mass.:
288.153
SMILES:
Clc1ccc(NC(=O)Nc2nccs2)cc1Cl
Structure:
Search PDB for entries with ligand similarity: