Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32287
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
17270±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32287
Synonyms:
(5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]-3-(2-oxolanylmethyl)-2-sulfanylidene-4-thiazolidinone | (5E)-5-[[5-(2-chlorophenyl)-2-furyl]methylene]-3-(tetrahydrofurfuryl)-2-thioxo-thiazolidin-4-one | (5E)-5-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one | 5-[5-(2-Chloro-phenyl)-furan-2-ylmethylene]-3-(tetrahydro-furan-2-ylmethyl)-2-thioxo-thiazolidin-4-one | MLS000568719 | SMR000175743 | cid_5759067
Type:
Small organic molecule
Emp. Form.:
C19H16ClNO3S2
Mol. Mass.:
405.918
SMILES:
Clc1ccccc1-c1ccc(\C=C2\SC(=S)N(CC3CCCO3)C2=O)o1
Structure:
Search PDB for entries with ligand similarity: