Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48902
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.000473±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48902
Synonyms:
2-[5-(3,4-Diethoxy-phenyl)-tetrazol-2-yl]-N-(4-methoxy-benzyl)-acetamide | 2-[5-(3,4-diethoxyphenyl)-1,2,3,4-tetrazol-2-yl]-N-[(4-methoxyphenyl)methyl]ethanamide | 2-[5-(3,4-diethoxyphenyl)-2-tetrazolyl]-N-[(4-methoxyphenyl)methyl]acetamide | 2-[5-(3,4-diethoxyphenyl)tetrazol-2-yl]-N-[(4-methoxyphenyl)methyl]acetamide | 2-[5-(3,4-diethoxyphenyl)tetrazol-2-yl]-N-p-anisyl-acetamide | MLS000070731 | SMR000003445 | cid_644486
Type:
Small organic molecule
Emp. Form.:
C21H25N5O4
Mol. Mass.:
411.4543
SMILES:
CCOc1ccc(cc1OCC)-c1nnn(CC(=O)NCc2ccc(OC)cc2)n1
Structure:
Search PDB for entries with ligand similarity: