Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48908
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00174±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48908
Synonyms:
2-hydroxy-4-keto-1-propyl-N-(4-pyridylmethyl)quinoline-3-carboxamide | 2-hydroxy-4-oxo-1-propyl-N-(pyridin-4-ylmethyl)-3-quinolinecarboxamide | 2-hydroxy-4-oxo-1-propyl-N-(pyridin-4-ylmethyl)quinoline-3-carboxamide | 2-oxidanyl-4-oxidanylidene-1-propyl-N-(pyridin-4-ylmethyl)quinoline-3-carboxamide | 4-Hydroxy-2-oxo-1-propyl-1,2-dihydro-quinoline-3-carboxylic acid (pyridin-4-ylmethyl)-amide | MLS000071813 | SMR000008723 | cid_648538
Type:
Small organic molecule
Emp. Form.:
C19H19N3O3
Mol. Mass.:
337.3725
SMILES:
CCCn1c2ccccc2c(O)c(C(=O)NCc2ccncc2)c1=O
Structure:
Search PDB for entries with ligand similarity: