Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48912
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00428±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48912
Synonyms:
3-[(2-fluorophenyl)methyl]-5-propyl-N-(pyridin-4-ylmethyl)-7-triazolo[4,5-d]pyrimidinamine | 3-[(2-fluorophenyl)methyl]-5-propyl-N-(pyridin-4-ylmethyl)-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine | 3-[(2-fluorophenyl)methyl]-5-propyl-N-(pyridin-4-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine | MLS000075664 | SMR000000629 | [3-(2-Fluoro-benzyl)-5-propyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-pyridin-4-ylmethyl-amine | [3-(2-fluorobenzyl)-5-propyl-triazolo[4,5-d]pyrimidin-7-yl]-(4-pyridylmethyl)amine | cid_651759
Type:
Small organic molecule
Emp. Form.:
C20H20FN7
Mol. Mass.:
377.4181
SMILES:
CCCc1nc(NCc2ccncc2)c2nnn(Cc3ccccc3F)c2n1
Structure:
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