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Target
D(1B) dopamine receptor
Ligand
BDBM48922
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00394±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48922
Synonyms:
3-[(6,6-dimethyl-2-methylsulfanyl-1,4,5,8-tetrahydropyrano[2,3]thieno[2,4-d]pyrimidin-4-yl)amino]propan-1-ol | 3-[[6,6-dimethyl-2-(methylthio)-1,4,5,8-tetrahydropyrano[2,3]thieno[2,4-d]pyrimidin-4-yl]amino]-1-propanol | 3-[[6,6-dimethyl-2-(methylthio)-1,4,5,8-tetrahydropyrano[2,3]thieno[2,4-d]pyrimidin-4-yl]amino]propan-1-ol | MLS000040064 | SMR000042781 | cid_662206
Type:
Small organic molecule
Emp. Form.:
C15H23N3O2S2
Mol. Mass.:
341.492
SMILES:
CSC1=Nc2sc3COC(C)(C)Cc3c2C(NCCCO)N1 |t:2|
Structure:
Search PDB for entries with ligand similarity: