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Target
D(1B) dopamine receptor
Ligand
BDBM48929
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.000516±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48929
Synonyms:
2-N-(4-methoxyphenyl)-6-[(1-methyltetrazol-5-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine | MLS000084541 | N2-(4-methoxyphenyl)-6-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanylmethyl]-1,3,5-triazine-2,4-diamine | N2-(4-methoxyphenyl)-6-[[(1-methyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine | SMR000047601 | [4-amino-6-[[(1-methyltetrazol-5-yl)thio]methyl]-s-triazin-2-yl]-(4-methoxyphenyl)amine | cid_666200
Type:
Small organic molecule
Emp. Form.:
C13H15N9OS
Mol. Mass.:
345.383
SMILES:
COc1ccc(Nc2nc(N)nc(CSc3nnnn3C)n2)cc1
Structure:
Search PDB for entries with ligand similarity: