Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48950
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00107±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48950
Synonyms:
1-butyl-5-keto-2-nicotinoylimino-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylic acid ethyl ester | 1-butyl-5-oxo-2-[oxo(3-pyridinyl)methyl]imino-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxylic acid ethyl ester | MLS000044284 | SMR000022066 | cid_2058645 | ethyl (2E)-1-butyl-5-oxo-2-[(pyridin-3-ylcarbonyl)imino]-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate | ethyl 1-butyl-5-oxidanylidene-2-pyridin-3-ylcarbonylimino-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate | ethyl 1-butyl-5-oxo-2-(pyridine-3-carbonylimino)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C24H23N5O4
Mol. Mass.:
445.4705
SMILES:
CCCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1cccnc1
Structure:
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