Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47800
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
20±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47800
Synonyms:
MLS000736409 | N'-[(E)-(2-fluorophenyl)methylidene]benzenesulfonohydrazide | N-[(2-fluorobenzylidene)amino]benzenesulfonamide | N-[(2-fluorophenyl)methylideneamino]benzenesulfonamide | SMR000338359 | cid_2172475
Type:
Small organic molecule
Emp. Form.:
C13H11FN2O2S
Mol. Mass.:
278.302
SMILES:
Fc1ccccc1C=NNS(=O)(=O)c1ccccc1 |w:8.9|
Structure:
Search PDB for entries with ligand similarity: