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Target
Zinc finger protein mex-5
Ligand
BDBM37138
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
7835±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM37138
Synonyms:
6-(4-methyl-1-piperazinyl)-2-(8-methyl-5-quinolinyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | 6-(4-methyl-1-piperazinyl)-2-(8-methyl-5-quinolinyl)benzo[de]isoquinoline-1,3-dione | 6-(4-methylpiperazin-1-yl)-2-(8-methylquinolin-5-yl)benzo[de]isoquinoline-1,3-dione | 6-(4-methylpiperazino)-2-(8-methyl-5-quinolyl)benzo[de]isoquinoline-1,3-quinone | MLS000089012 | SMR000073309 | cid_2193273
Type:
Small organic molecule
Emp. Form.:
C27H24N4O2
Mol. Mass.:
436.5051
SMILES:
CN1CCN(CC1)c1ccc2C(=O)N(C(=O)c3cccc1c23)c1ccc(C)c2ncccc12
Structure:
Search PDB for entries with ligand similarity: