Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM53082
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM53082
Synonyms:
4-Chloro-7-methyl-3-(phenyl-hydrazono)-1,3-dihydro-indol-2-one | 4-chloranyl-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(2-phenylhydrazinyl)indol-2-one | 4-chloro-7-methyl-3-(N'-phenylhydrazino)indol-2-one | 4-chloro-7-methyl-3-(phenylhydrazo)-2-indolone | MLS001209448 | SMR000513316 | cid_5752240
Type:
Small organic molecule
Emp. Form.:
C15H12ClN3O
Mol. Mass.:
285.728
SMILES:
Cc1ccc(Cl)c2=C(NNc3ccccc3)C(=O)N=c12 |c:6,t:19|
Structure:
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