Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM53237
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
53947±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM53237
Synonyms:
1-[4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-1,4-dioxobutyl]-4-piperidinecarboxylic acid ethyl ester | 1-[4-keto-4-[N'-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazino]butanoyl]isonipecotic acid ethyl ester | MLS000924795 | SMR000623669 | cid_24789610 | ethyl 1-[4-[2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazinyl]-4-oxidanylidene-butanoyl]piperidine-4-carboxylate | ethyl 1-[4-[2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazinyl]-4-oxobutanoyl]piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C22H27N7O4
Mol. Mass.:
453.4943
SMILES:
CCOC(=O)C1CCN(CC1)C(=O)CCC(=O)NNc1nc2ccccc2c2nc(C)nn12
Structure:
Search PDB for entries with ligand similarity: