Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52470
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52470
Synonyms:
1-(3-chloro-2-methyl-phenyl)-2-methyl-3-(2-thienylsulfonyl)isothiourea | MLS000416749 | N-(3-chloro-2-methylphenyl)-N'-thiophen-2-ylsulfonylcarbamimidothioic acid methyl ester | SMR000241714 | cid_5674849 | methyl N-(3-chloranyl-2-methyl-phenyl)-N'-thiophen-2-ylsulfonyl-carbamimidothioate | methyl N-(3-chloro-2-methylphenyl)-N'-thiophen-2-ylsulfonylcarbamimidothioate
Type:
Small organic molecule
Emp. Form.:
C13H13ClN2O2S3
Mol. Mass.:
360.903
SMILES:
CSC(NS(=O)(=O)c1cccs1)=Nc1cccc(Cl)c1C |w:12.13|
Structure:
Search PDB for entries with ligand similarity: