Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52507
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
37766±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52507
Synonyms:
(3E)-2-amino-5-methyl-3-(phenylhydrazinylidene)-7-pyrazolo[1,5-a]pyrimidinone | (3E)-2-amino-5-methyl-3-(phenylhydrazinylidene)pyrazolo[1,5-a]pyrimidin-7-one | (3E)-2-amino-5-methyl-3-(phenylhydrazono)pyrazolo[1,5-a]pyrimidin-7-one | (3E)-2-azanyl-5-methyl-3-(phenylhydrazinylidene)pyrazolo[1,5-a]pyrimidin-7-one | 2-amino-5-methyl-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one | MLS000705747 | SMR000230975 | cid_15945760
Type:
Small organic molecule
Emp. Form.:
C13H12N6O
Mol. Mass.:
268.274
SMILES:
Cc1cc(=O)n2[nH]c(N)c(N=Nc3ccccc3)c2n1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: