Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM29658
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM29658
Synonyms:
MLS000557330 | N-[3-Cyano-1-furan-2-ylmethyl-8-methyl-10-oxo-1,10-dihydro-1,9,10a-triaza-anthracen-(2Z)-ylidene]-3- methyl-benzamide | N-[3-cyano-1-(2-furanylmethyl)-10-methyl-5-oxo-2-dipyrido[3,4-c:1',2'-f]pyrimidinylidene]-3-methylbenzamide | N-[3-cyano-1-(2-furfuryl)-5-keto-10-methyl-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]-3-methyl-benzamide | N-[3-cyano-1-(furan-2-ylmethyl)-10-methyl-5-oxidanylidene-dipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]-3-methyl-benzamide | N-[3-cyano-1-(furan-2-ylmethyl)-10-methyl-5-oxodipyrido[3,4-c:1',2'-f]pyrimidin-2-ylidene]-3-methylbenzamide | SMR000148247 | cid_4522020
Type:
Small organic molecule
Emp. Form.:
C26H19N5O3
Mol. Mass.:
449.4608
SMILES:
Cc1cccc(c1)C(=O)\N=c1/c(cc2c(nc3c(C)cccn3c2=O)n1Cc1ccco1)C#N
Structure:
Search PDB for entries with ligand similarity: