Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM56223
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
50000±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM56223
Synonyms:
4-[(2,4-dimethylanilino)-oxomethyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester | 4-[(2,4-dimethylphenyl)carbamoyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester | MLS000118942 | SMR000095882 | cid_5308454 | ethyl 4-[(2,4-dimethylphenyl)carbamoyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H22N2O3
Mol. Mass.:
314.3789
SMILES:
CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(C)cc2C)c1C
Structure:
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