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Target
Streptokinase A
Ligand
BDBM56996
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56996
Synonyms:
1-(4-imidazol-1-yl-6-phenyl-1,3,5-triazin-2-yl)azepane | 1-(4-imidazol-1-yl-6-phenyl-s-triazin-2-yl)azepane | 1-[4-(1-imidazolyl)-6-phenyl-1,3,5-triazin-2-yl]azepane | 1-[4-(1H-imidazol-1-yl)-6-phenyl-1,3,5-triazin-2-yl]azepane | MLS000043957 | SMR000021368 | cid_1266902
Type:
Small organic molecule
Emp. Form.:
C18H20N6
Mol. Mass.:
320.3916
SMILES:
C1CCCN(CC1)c1nc(nc(n1)-n1ccnc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: