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Target
Kappa-type opioid receptor
Ligand
BDBM48095
Substrate
n/a
Meas. Tech.
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
IC50
13900±n/a nM
Citation
 PubChem, PC uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM48095
Synonyms:
MLS000713975 | N-[4-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]phenyl]sulfonylacetamide | N-[4-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]phenyl]sulfonylethanamide | N-[4-[(7-nitrobenzofurazan-4-yl)amino]phenyl]sulfonylacetamide | SMR000273456 | cid_2836581
Type:
Small organic molecule
Emp. Form.:
C14H11N5O6S
Mol. Mass.:
377.332
SMILES:
CC(=O)NS(=O)(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1
Structure:
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