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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62158
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62158
Synonyms:
4-(azepan-1-ylcarbonyl)-N-(2,5-dimethoxyphenyl)-1,2,5-trimethyl-pyrrole-3-sulfonamide | 4-(azepane-1-carbonyl)-N-(2,5-dimethoxyphenyl)-1,2,5-trimethyl-pyrrole-3-sulfonamide | 4-(azepane-1-carbonyl)-N-(2,5-dimethoxyphenyl)-1,2,5-trimethylpyrrole-3-sulfonamide | 4-[1-azepanyl(oxo)methyl]-N-(2,5-dimethoxyphenyl)-1,2,5-trimethyl-3-pyrrolesulfonamide | MLS001096203 | SMR000630930 | cid_20945667
Type:
Small organic molecule
Emp. Form.:
C22H31N3O5S
Mol. Mass.:
449.564
SMILES:
COc1ccc(OC)c(NS(=O)(=O)c2c(C)n(C)c(C)c2C(=O)N2CCCCCC2)c1
Structure:
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