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Target
Trans-activator protein BZLF1
Ligand
BDBM62412
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA
IC50
111248±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA PubChem Bioassay (2010)[AID] 
Target
Name:
Trans-activator protein BZLF1
Synonyms:
BZLF1 | BZLF1_EBVB9 | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
26856.37
Organism:
Human herpesvirus 4
Description:
gi_82503229
Residue:
245
Sequence:
MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF
  
Inhibitor
Name:
BDBM62412
Synonyms:
2-[2-(4-bromophenyl)-2-keto-ethyl]-1-keto-8,9-dihydro-7H-pyrimido[5,4-a]pyrrolizine-5-carbonitrile | 2-[2-(4-bromophenyl)-2-oxidanylidene-ethyl]-1-oxidanylidene-8,9-dihydro-7H-pyrimido[5,4-a]pyrrolizine-5-carbonitrile | 2-[2-(4-bromophenyl)-2-oxoethyl]-1-oxo-8,9-dihydro-7H-pyrimido[5,4-a]pyrrolizine-5-carbonitrile | MLS000068766 | SMR000038026 | cid_659700
Type:
Small organic molecule
Emp. Form.:
C18H13BrN4O2
Mol. Mass.:
397.225
SMILES:
Brc1ccc(cc1)C(=O)Cn1cnc2c(C#N)n3CCCc3c2c1=O
Structure:
Search PDB for entries with ligand similarity: