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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM64544
Substrate
n/a
Meas. Tech.
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
33385±1470 nM
Citation
 PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM64544
Synonyms:
7-[(1,3-benzothiazol-2-ylamino)-(2-furanyl)methyl]-8-quinolinol | 7-[(1,3-benzothiazol-2-ylamino)-(2-furyl)methyl]quinolin-8-ol | 7-[(1,3-benzothiazol-2-ylamino)-(furan-2-yl)methyl]quinolin-8-ol | MLS000089236 | SMR000060957 | cid_2998355
Type:
Small organic molecule
Emp. Form.:
C21H15N3O2S
Mol. Mass.:
373.428
SMILES:
Oc1c(ccc2cccnc12)C(Nc1nc2ccccc2s1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: