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Target
Inward rectifier potassium channel 2
Ligand
BDBM65861
Substrate
n/a
Meas. Tech.
Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1
IC50
23588±8904 nM
Citation
 PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay (2010)[AID] 
Target
Name:
Inward rectifier potassium channel 2
Synonyms:
Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48383.35
Organism:
Mus musculus
Description:
gi_6680530
Residue:
428
Sequence:
MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPRPLRRESEI
  
Inhibitor
Name:
BDBM65861
Synonyms:
1-{[3-(3-phenoxyphenoxy)propyl]amino}-2-propanol ethanedioate (salt) | MLS000664678 | SMR000296405 | cid_2976394 | ethanedioic acid;1-[3-(3-phenoxyphenoxy)propylamino]propan-2-ol | oxalic acid;1-[3-(3-phenoxyphenoxy)propylamino]-2-propanol | oxalic acid;1-[3-(3-phenoxyphenoxy)propylamino]propan-2-ol
Type:
Small organic molecule
Emp. Form.:
C18H23NO3
Mol. Mass.:
301.3801
SMILES:
CC(O)CNCCCOc1cccc(Oc2ccccc2)c1
Structure:
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