Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66223
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66223
Synonyms:
MLS000034501 | N-[4-[4-(2-furoyl)piperazino]phenyl]thiophene-2-carboxamide | N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]thiophene-2-carboxamide | N-[4-[4-(furan-2-ylcarbonyl)piperazin-1-yl]phenyl]thiophene-2-carboxamide | N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]-2-thiophenecarboxamide | SMR000014303 | Thiophene-2-carboxylic acid {4-[4-(furan-2-carbonyl)-piperazin-1-yl]-phenyl}-amide | cid_645161
Type:
Small organic molecule
Emp. Form.:
C20H19N3O3S
Mol. Mass.:
381.448
SMILES:
O=C(Nc1ccc(cc1)N1CCN(CC1)C(=O)c1ccco1)c1cccs1
Structure:
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