Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66270
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66270
Synonyms:
3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide | 3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)coumarilamide | 3-(cyclopropylcarbonylamino)-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide | 3-[(cyclopropylcarbonyl)amino]-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide | 3-[[cyclopropyl(oxo)methyl]amino]-N-(4-methoxyphenyl)-2-benzofurancarboxamide | MLS000092988 | SMR000028624 | cid_3243757
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4
Mol. Mass.:
350.3679
SMILES:
COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C2CC2)cc1
Structure:
Search PDB for entries with ligand similarity: