Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66017
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66017
Synonyms:
2-chloranyl-N-(2,6-dimethylphenyl)-3-oxidanylidene-3-phenyl-propanamide | 2-chloro-N-(2,6-dimethylphenyl)-3-keto-3-phenyl-propionamide | 2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide | MLS001176107 | SMR000595561 | cid_4484064
Type:
Small organic molecule
Emp. Form.:
C17H16ClNO2
Mol. Mass.:
301.767
SMILES:
Cc1cccc(C)c1NC(=O)C(Cl)C(=O)c1ccccc1
Structure:
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