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Target
Bcl-2-like protein 11
Ligand
BDBM66832
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66832
Synonyms:
MLS001029335 | N-(4-fluorobenzyl)-3-[3-keto-5-[[2-keto-2-(tetrahydrofurfurylamino)ethyl]thio]-2H-imidazo[1,2-c]quinazolin-2-yl]propionamide | N-[(4-fluorophenyl)methyl]-3-[3-oxidanylidene-5-[2-oxidanylidene-2-(oxolan-2-ylmethylamino)ethyl]sulfanyl-2H-imidazo[1,2-c]quinazolin-2-yl]propanamide | N-[(4-fluorophenyl)methyl]-3-[3-oxo-5-[2-oxo-2-(oxolan-2-ylmethylamino)ethyl]sulfanyl-2H-imidazo[1,2-c]quinazolin-2-yl]propanamide | N-[(4-fluorophenyl)methyl]-3-[3-oxo-5-[[2-oxo-2-(2-oxolanylmethylamino)ethyl]thio]-2H-imidazo[1,2-c]quinazolin-2-yl]propanamide | SMR000634268 | cid_22589549
Type:
Small organic molecule
Emp. Form.:
C27H28FN5O4S
Mol. Mass.:
537.606
SMILES:
Fc1ccc(CNC(=O)CCC2N=C3N(C2=O)C(SCC(=O)NCC2CCCO2)=Nc2ccccc32)cc1 |c:12,30|
Structure:
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