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Target
Protein LANA1
Ligand
BDBM73669
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction
EC50
>75000±n/a nM
Citation
 PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein LANA1
Synonyms:
LANA | LANA1 | LANA1_HHV8P
Type:
Enzyme Catalytic Domain
Mol. Mass.:
131093.36
Organism:
Human herpesvirus 8
Description:
Q9QR71
Residue:
1129
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
  
Inhibitor
Name:
BDBM73669
Synonyms:
4-[[2-methylol-5-[(4-morpholinosulfonylphenyl)carbamoyl]benzoyl]amino]piperidine-1-carboxylic acid ethyl ester | 4-[[[2-(hydroxymethyl)-5-[[4-(4-morpholinylsulfonyl)anilino]-oxomethyl]phenyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester | MLS000675313 | SMR000314035 | cid_16194343 | ethyl 4-[[2-(hydroxymethyl)-5-[(4-morpholin-4-ylsulfonylphenyl)carbamoyl]benzoyl]amino]piperidine-1-carboxylate | ethyl 4-[[2-(hydroxymethyl)-5-[(4-morpholin-4-ylsulfonylphenyl)carbamoyl]phenyl]carbonylamino]piperidine-1-carboxylate | ethyl 4-{[2-(hydroxymethyl)-5-({[4-(morpholin-4-ylsulfonyl)phenyl]amino}carbonyl)benzoyl]amino}piperidine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C27H34N4O8S
Mol. Mass.:
574.646
SMILES:
CCOC(=O)N1CCC(CC1)NC(=O)c1cc(ccc1CO)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: