Target

Ligand

Substrate

Meas. Tech.

Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay

Citation

 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Mitochondrial import inner membrane translocase subunit TIM10

Synonyms:

MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...

Type:

Enzyme Catalytic Domain

Mol. Mass.:

10303.50

Organism:

Saccharomyces cerevisiae S288c

Description:

gi_285809906

Residue:

93

Sequence:

MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM59704

Synonyms:

1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea | 1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]urea | 1-(3,4-dichlorophenyl)-3-[4-[(3,4-dimethylisoxazol-5-yl)sulfamoyl]phenyl]urea | 4-({[(3,4-dichlorophenyl)amino]carbonyl}amino)-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide | MLS000050956 | SMR000078689 | cid_1188014

Type:

Small organic molecule

Emp. Form.:

C18H16Cl2N4O4S

Mol. Mass.:

455.315

SMILES:

Cc1noc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c1C

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least: