Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM67799
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
210±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM67799
Synonyms:
2-[2,5-Dioxo-1-(4-propoxy-phenyl)-pyrrolidin-3-yl]-1-(4-fluoro-phenyl)-3-methyl-isothiourea | 2-[2,5-diketo-1-(4-propoxyphenyl)pyrrolidin-3-yl]-1-(4-fluorophenyl)-3-methyl-isothiourea | MLS000528545 | N-(4-fluorophenyl)-N'-methylcarbamimidothioic acid [2,5-dioxo-1-(4-propoxyphenyl)-3-pyrrolidinyl] ester | SMR000118123 | [2,5-bis(oxidanylidene)-1-(4-propoxyphenyl)pyrrolidin-3-yl] N-(4-fluorophenyl)-N'-methyl-carbamimidothioate | [2,5-dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl] N-(4-fluorophenyl)-N'-methylcarbamimidothioate | cid_3126858
Type:
Small organic molecule
Emp. Form.:
C21H22FN3O3S
Mol. Mass.:
415.481
SMILES:
CCCOc1ccc(cc1)-n1c(O)cc(SC(NC)=Nc2ccc(F)cc2)c1O |w:19.20|
Structure:
Search PDB for entries with ligand similarity: