Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM67807
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
290±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM67807
Synonyms:
5-(4-methylbenzyl)-7-(trifluoromethyl)-3,3a-dihydro-1H-thiazolo[3,4-a]quinoxalin-4-one | 5-(4-methylbenzyl)-7-(trifluoromethyl)-3,3a-dihydro[1,3]thiazolo[3,4-a]quinoxalin-4(5H)-one | 5-[(4-methylphenyl)methyl]-7-(trifluoromethyl)-3,3a-dihydro-1H-[1,3]thiazolo[3,4-a]quinoxalin-4-one | 5-[(4-methylphenyl)methyl]-7-(trifluoromethyl)-3,3a-dihydro-1H-thiazolo[3,4-a]quinoxalin-4-one | MLS000541396 | SMR000126254 | cid_3806160
Type:
Small organic molecule
Emp. Form.:
C19H17F3N2OS
Mol. Mass.:
378.411
SMILES:
Cc1ccc(CN2C(=O)C3CSCN3c3ccc(cc23)C(F)(F)F)cc1
Structure:
Search PDB for entries with ligand similarity: