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Target
X-box-binding protein 1
Ligand
BDBM53947
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
6570±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM53947
Synonyms:
4-[(N'E)-N'-(6-ketocyclohexa-2,4-dien-1-ylidene)hydrazino]-5-methyl-2-[4-(p-tolyl)thiazol-2-yl]-2-pyrazolin-3-one | 5-methyl-2-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-4-[(2E)-2-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)hydrazinyl]-4H-pyrazol-3-one | 5-methyl-2-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-4-[(2E)-2-(6-oxocyclohexa-2,4-dien-1-ylidene)hydrazinyl]-4H-pyrazol-3-one | 5-methyl-2-[4-(4-methylphenyl)-2-thiazolyl]-4-[(2E)-2-(6-oxo-1-cyclohexa-2,4-dienylidene)hydrazinyl]-4H-pyrazol-3-one | MLS000713300 | SMR000272781 | cid_5720147
Type:
Small organic molecule
Emp. Form.:
C20H17N5O2S
Mol. Mass.:
391.446
SMILES:
Cc1[nH]n(-c2nc(cs2)-c2ccc(C)cc2)c(=O)c1N=Nc1ccccc1O |w:19.21|
Structure:
Search PDB for entries with ligand similarity: