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Target
Bcl-2-related protein A1
Ligand
BDBM78782
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM78782
Synonyms:
4-[1-[(3-fluorophenyl)methyl]-2,4-bis(oxidanylidene)quinazolin-3-yl]-N-[1-(phenylmethyl)piperidin-4-yl]butanamide | 4-[1-[(3-fluorophenyl)methyl]-2,4-dioxo-3-quinazolinyl]-N-[1-(phenylmethyl)-4-piperidinyl]butanamide | MLS000730457 | N-(1-benzyl-4-piperidyl)-4-[1-(3-fluorobenzyl)-2,4-diketo-quinazolin-3-yl]butyramide | N-(1-benzylpiperidin-4-yl)-4-[1-(3-fluorobenzyl)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]butanamide | N-(1-benzylpiperidin-4-yl)-4-[1-[(3-fluorophenyl)methyl]-2,4-dioxoquinazolin-3-yl]butanamide | SMR000308733 | cid_16193615
Type:
Small organic molecule
Emp. Form.:
C31H33FN4O3
Mol. Mass.:
528.6171
SMILES:
Fc1cccc(Cn2c3ccccc3c(=O)n(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)c2=O)c1
Structure:
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