Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM65630
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
3850±344 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM65630
Synonyms:
2-[[4-(diphenylamino)phenyl]methylideneamino]guanidine;nitric acid | MLS001172717 | SMR000587877 | cid_24761819 | nitric acid;2-[(E)-[4-(N-phenylanilino)benzylidene]amino]guanidine | nitric acid;2-[[4-(N-phenylanilino)benzylidene]amino]guanidine | nitric acid;2-[[4-(N-phenylanilino)phenyl]methylideneamino]guanidine
Type:
Small organic molecule
Emp. Form.:
C20H19N5
Mol. Mass.:
329.3984
SMILES:
[#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1ccc(cc1)-[#7](-c1ccccc1)-c1ccccc1 |w:4.3|
Structure:
Search PDB for entries with ligand similarity: