Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM79334
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
7490±289 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM79334
Synonyms:
MLS002391556 | N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide;2,2,2-trifluoroacetic acid | N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolyl)benzamide;2,2,2-trifluoroacetic acid | N-[3-(dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide;2,2,2-trifluoroacetic acid | N-[3-(dimethylamino)propyl]-4-(8-oxidanylquinolin-6-yl)benzamide;2,2,2-tris(fluoranyl)ethanoic acid | SMR001355524 | cid_44143208
Type:
Small organic molecule
Emp. Form.:
C21H23N3O2
Mol. Mass.:
349.4262
SMILES:
CN(C)CCCNC(=O)c1ccc(cc1)-c1cc(O)c2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: