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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM53895
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
>80000±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM53895
Synonyms:
4-Methyl-N-{4-methyl-5-[1-phenyl-meth-(E)-ylidene-hydrazinocarbonyl]-thiazol-2-yl}-benzenesulfonamide | 4-methyl-2-[(4-methylphenyl)sulfonylamino]-N-[(phenylmethylene)amino]-5-thiazolecarboxamide | 4-methyl-2-[(4-methylphenyl)sulfonylamino]-N-[(phenylmethylidene)amino]-1,3-thiazole-5-carboxamide | MLS000587370 | N-(benzalamino)-4-methyl-2-(tosylamino)thiazole-5-carboxamide | N-(benzylideneamino)-4-methyl-2-[(4-methylphenyl)sulfonylamino]-1,3-thiazole-5-carboxamide | SMR000211423 | cid_1417257
Type:
Small organic molecule
Emp. Form.:
C19H18N4O3S2
Mol. Mass.:
414.501
SMILES:
Cc1nc(NS(=O)(=O)c2ccc(C)cc2)sc1C(=O)NN=Cc1ccccc1
Structure:
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