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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM80934
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
>80000±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM80934
Synonyms:
(2,6-dichlorobenzyl)-(4-pyrrolidinophenyl)amine | (2,6-dichlorobenzyl)[4-(1-pyrrolidinyl)phenyl]amine | MLS000662049 | N-[(2,6-dichlorophenyl)methyl]-4-(1-pyrrolidinyl)aniline | N-[(2,6-dichlorophenyl)methyl]-4-pyrrolidin-1-ylaniline | N-[[2,6-bis(chloranyl)phenyl]methyl]-4-pyrrolidin-1-yl-aniline | SMR000292692 | cid_893102
Type:
Small organic molecule
Emp. Form.:
C17H18Cl2N2
Mol. Mass.:
321.244
SMILES:
Clc1cccc(Cl)c1CNc1ccc(cc1)N1CCCC1
Structure:
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